
The pharmacokinetic study was conducted in healthy human volunteers and compared the drug exposure profile of arbaclofen, under both fasted and fed conditions, following a single oral administration of a 5mg dose. Arbaclofen contains the purified R-isomer form of the previously approved drug baclofen (which is an equal mixture of the S- and R-isomers). In addition, this study compared the drug exposure of arbaclofen (5mg), in terms of both the S- and R-isomer forms of baclofen, with a single 10mg oral dose of Lioresal® (a marketed form of racemic baclofen)... AGI Therapeutics' Press Release -