DIABETES CIES SEARCH ENGINE [SELECTED WEBSITES]

Blog Archive

Friday, March 21, 2008

Sirtris' SIRT1 Activators; Patent Covers First NCE to Enter Human Clinical Trials

March 19, 2008--Sirtris Pharmaceuticals, Inc. (NASDAQ: SIRT), a biopharmaceutical company focused on discovering and developing small molecule drugs to treat diseases of aging such as Type 2 Diabetes, announced that the United States Patent Office issued to Sirtris the first patent covering a broad class of compounds that activate the enzyme SIRT1. Several Sirtris compounds--or new chemical entities (NCEs)--from this class lower glucose and improve insulin sensitivity in preclinical models of Type 2 Diabetes. The patent covers the first NCE that Sirtris plans to take into a human clinical safety trial in the first half of 2008... Sirtris' Press Release -