Blog Archive
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2008
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March
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- Medtronic : Announces Sales Milestone of One Milli...
- AgaMatrix : WaveSense Europe Launches Jazz Glucose...
- Boston Scientific : TAXUS Express Stent Shows Simi...
- SemBioSys : toxicology study for safflower-produce...
- Keryx Biopharmaceuticals : Termination of SUN-MACR...
- Atherotech 's VAP Test Helps Researchers Uncover B...
- Generex Biotechnology : Its Protocol for Metcontr...
- Echo Therapeutics : Positive Results from Symphony...
- Oramed Pharmaceuticals : Phase 2A Trials of Its Or...
- MacroChem, Pexiganan Phase 3 Study Results for Top...
- MannKind : Response to Recent Market Events
- Generex Oral-lyn, another regulatory approval to c...
- Metabolon and EGIR, Partnership to Accelerate Pre-...
- Mercury Therapeutics : series of indirect AMPK act...
- Sirtris' SIRT1 Activators; Patent Covers First NCE...
- DiObex and Camurus , Agreement for the Development...
- Lilly and Transition Therapeutics, Licensing and C...
- Synvista Therapeutics, Newly Published Data Demons...
- PPD, Takeda's NDA Filing of Alogliptin with U.S. F...
- Alizyme's cetilistat Phase III development program...
- Axis-Shield, HbA1c Test on Abbott's AXSYM Analyser
- Marcadia Biotech and Merck, strategic collaboration
- OSI Pharmaceuticals : the Prior Revocation of Its ...
- Hollis-Eden Pharmaceuticals, Positive Preliminary ...
- Diamyd Medical, Authorization to Begin Phase III S...
- Sernova, First Regulatory Step Towards Clinical Tr...
- Cannasat Therapeutics, Update on Patent Applicatio...
- Living Cell Technologies' DiabeCell Clinical Trial...
- Nitric BioTherapeutics, Phase II Clinical Trial fo...
- Oramed Pharmaceuticalsals, Phase 1B Clinical Trial...
- Abbott's FreeStyle Navigator Continuous Glucose Mo...
- Elixir Pharmaceuticals, new data on the role of gh...
- Akesis Pharmaceuticals, First Patient in Phase IIa...
- Oculus Innovative Sciences, Phase II Data with Mic...
- Alkermes, Eli Lilly, Termination of AIR (Inhaled) ...
- PLC Systems' RenalGuard Therapy and RenalGuard Sys...
- Novocell, Successful Use of Stem Cells to Generate...
- Novartis Eucreas combination of Galvus® and metfor...
- Johnson & Johnson Diabetes Institute, New Center T...
- Metabasis Therapeutics, Proof-of-Concept Clinical ...
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March
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Friday, March 21, 2008
Sirtris' SIRT1 Activators; Patent Covers First NCE to Enter Human Clinical Trials
March 19, 2008--Sirtris Pharmaceuticals, Inc. (NASDAQ: SIRT), a biopharmaceutical company focused on discovering and developing small molecule drugs to treat diseases of aging such as Type 2 Diabetes, announced that the United States Patent Office issued to Sirtris the first patent covering a broad class of compounds that activate the enzyme SIRT1. Several Sirtris compounds--or new chemical entities (NCEs)--from this class lower glucose and improve insulin sensitivity in preclinical models of Type 2 Diabetes. The patent covers the first NCE that Sirtris plans to take into a human clinical safety trial in the first half of 2008... Sirtris' Press Release -